Our new article entitled « Complementary biophysical tools to investigate lipid specificity in the interaction between bioactive molecules and the plasma membrane: A review » is now available in the journal Biochimica et Biophysica Acta (BBA) – Biomembranes.
The plasma membrane is a key component of the cell and understanding the way in which biomolecules interact with this component is crucial. Before, the overall trend was thinking about an interaction between a molecule and its receptor located on the membrane. However, recent works showed that the interactions could occur with the lipid phase of the membrane instead of receptors and in this context, the lipid specificity of the interaction was also a key factor.
In this article, we review the biomimetic approach and its related biophysical tools to investigate lipid specificity in the interaction between bioactive molecules and the plasma membrane.